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Jewish cancer genetics

gene brca

Jewish cancer genetics

One in 40 people of Ashkenazi Jewish ancestry (2.5%) carry a mutation (fault) in the genes BRCA1 or BRCA2. Mutations in these genes cause an increased risk of breast, ovarian, prostate and male breast cancer. Individuals with BRCA mutations often consider increased cancer screening as well as risk-reducing surgeries to lower their risks.

Individuals are more likely to have a BRCA mutation if they have a personal or family history of:

Breast cancer diagnosed at an early age (before age 45)

Bilateral breast cancer

Ovarian cancer

Male breast cancer

Multiple relatives with breast, prostate, pancreatic or ovarian cancer.

For more information regarding BRCA mutations please click here

Insurance

At present there is a moratorium in the UK which prevents insurance companies from asking about predictive/carrier testing. While this is not law it has been renewed several times and is next due for review in 2019.

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