Recommended Referral Criteria & Form

Recommended referral criteria for breast cancer

Any woman concerned about her family history should be referred for a comprehensive risk assessment, and screening recommendations.

Genetic testing should be discussed with patients who have been diagnosed with breast cancer AND meet one of the following criteria:

• Jewish Ancestry
• Diagnosed <  age 45
• Bilateral breast cancer < age 60
• Triple negative tumour
• Ovarian cancer
• Male breast cancer
• Parent/child or sibling meeting above criteria 

Recommended referral criteria for colorectal cancer

Genetic testing should be discussed with patients who have been diagnosed with colorectal cancer AND meet one of the following criteria:

• Abnormal tumour testing (MSIH or absent IHC)
• Diagnosed < age 50
• Diagnosed < age 60 AND TILS, signet ring formation or mucinous
• Endometrial / ovarian cancer
• Multiple bowel polyps
• 2+ relatives with colorectal cancer / endometrial or ovarian cancer

OR

• Personal history of multiple Adenomas (10+)

Recommended referral criteria for prostate cancer

Genetic testing should be discussed with patients who have been diagnosed with prostate cancer AND meet one of the following criteria:

Diagnosed under 55 years

Metastatic prostate cancer

Family history of cancer:

• 2 FDR with Prostate cancer
• 2 FDR / SDR with breast or ovarian cancer
• 2 FDR/SDR with bowel or womb cancer
• 1 FDR or SDR with male breast cancer, ovarian cancer, bilateral breast cancer, bowel cancer diagnosed before 50, womb cancer diagnosed before 50
• 1 FDR with breast, ovarian or prostate cancer AND Ashkenazi Jewish ancestry

Recommended referral criteria for ovarian cancer

Any patient with high grade serous ovarian cancer should be referred for genetic testing.