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OvarianGene looks at 9 genes which cause an increased risk of ovarian cancer.
The following genes are tested:
OvarianGene is a genetic test for women diagnosed with ovarian cancer which examines the DNA code for 9 genes known to cause an increased risk of ovarian cancer. It is performed on a blood sample and results take 3-4 weeks.
What is hereditary ovarian cancer?
Ovarian cancer is the fifth most common cancer in women. In the general population women have a 1.5% risk of ovarian cancer, with 75% being diagnosed after the age of 55. Most ovarian cancers occur by chance, however up to 20% is hereditary and in some families it may be possible to find the genetic change (mutation) which is responsible for the cancer. This allows appropriate cancer screening and risk- reducing options.
How do I know if I am at risk?
Any individual with high grade serious ovarian cancer is eligible for genetic testing.
It is important to be aware that hereditary ovarian cancer can be present on either the maternal (mother’s) or paternal (father’s) side of the family.
How can genetic testing help?
Genetic testing can help determine the best chemotherapies as well as to determine the risk of cancer within a family and guide appropriate cancer screening. Depending on the specific genetic risk different screening tests can be arranged and risk- reducing strategies can be considered.
What will the test show?
There are 3 possible results:
- A mutation is found in one of the genes which is known to increase the risk of ovarian cancer. Specific chemotherapy may be recommended. Increased screening and/or risk-reducing techniques will be recommended.
- A genetic variation is found, but whether or not this is the definite cause of cancer is unknown. Screening will be recommended based on the family history.
- No mutation is found. It is possible that there may be an undetectable mutation or a mutation in a different gene. Cancer screening/risk reducing techniques may still be beneficial.
What does it mean if I have a mutation?
If you have a mutation this explains why you have developed ovarian cancer and means that you may benefit from specific treatments as well as possibly being at increased risk of other cancers. Your exact risks will depend on which gene mutation has been found. Extra screening and/or risk- reducing strategies will be discussed. It will also be possible to offer predictive testing to other people in your family to see if they also have the mutation.
Price
The cost for OvarianGene is £1500 which includes pre- and post-test counselling.
Book an initial 1 hour consultation for only £150 and find out if you are at risk
Book your consultation now
