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Predictive genetic testing

In some families, the genetic cause of the cancer may be known. In these families, a relative has already had genetic testing which has shown a mutation (fault) in one of their cancer genes. 

Predictive testing for someone who is healthy is then possible to see if they have inherited the faulty cancer gene in the family. Not everyone with a faulty cancer gene will develop cancer but their risk is increased.

Predictive testing gives relatives a definitive answer. Either:

1. The mutation is not present so there is no increased risk of cancer.

-  Their children cannot have inherited the mutation and are also not at increased risk of cancer

2. The mutation is found and the individual has an increased risk of cancer. Increased cancer screening and risk reducing options may be helpful.

Who can have predictive testing?

Any blood relative of someone with a known cancer gene mutation can have predictive testing.

The brothers, sisters, parents, and children of someone with an inherited cancer gene mutation each have a 50% chance of also carrying the gene mutation. While aunts, uncles, nieces and nephews have 25% and cousins have a 12.5% chance. Cancer gene mutations do not skip a generation so if a parent has normal genetic testing their children do not need to be tested. However, not everyone with a cancer mutation will develop cancer which is why cancer may appear to have skipped a generation in some families.

In order to offer predictive testing, we will need a copy of the genetic test report from the relative who has had testing. This ensures that we know what to test for.

Genetic testing process

If you would like to have testing or to learn more about your risks you will be asked to complete an online family history questionnaire and provide a copy of your relative’s test report. A Genetic Counsellor will then explain what the faulty gene is, how it is inherited, the associated cancer risks, and options for cancer screening or risk-reducing options.

The Genetic Counsellor will also explore the emotional impact of genetic testing. Not everyone will decide to have genetic testing and the results can have an impact on family dynamics. The decision whether or not to have testing is a very personal one and this will be explored in the genetic counselling consultation.

If you decide to proceed with genetic testing you will be asked to provide a blood or saliva sample. Results will be available approximately three weeks later and a consultation will be made with the Genetic Counsellor at this time. If testing shows you have the familial mutation, then the Genetic Counsellor will arrange further screening and discussion of risk reducing options.

Book an initial 1 hour consultation for only £150 and find out if you are at risk

Book your consultation now

Insurance and financial information

Some individuals may be concerned about difficulties obtaining insurance coverage following genetic testing. This does not need to be a concern as the Code on Genetic Testing and Insurance ensures that individuals do not have to disclose cancer predictive test results. More information can be found at

Individuals with a family history of cancer often question:

Am I at risk?
Are my children at risk?
What can I do to detect or reduce my risk of cancer?
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Fill out your details and one of our friendly staff will call you back within 1 working day to book your consultation with a Genetic Counsellor.

or if you prefer, call 0800 331 7177 to book now

Genetic Counselling Services
If you have a family history of cancer
Complete a referral
Refer a patient or yourself

Do you want your genes tested for cancer risk?

Book an initial 1 hour consultation for only £150 and find out if you are at risk

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